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The Role of PCR in Diagnosis of a Rare Appendicular Tuberculosis and Mini Literature Review

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dc.contributor.author Sengal, Asmerom Tesfamariam
dc.contributor.author Mohamedani, Ahmed Abdalla
dc.contributor.author Hussein, Hanan Hasaan
dc.contributor.author Kamal, Alaa
dc.date.accessioned 2017-10-06T16:54:34Z
dc.date.available 2017-10-06T16:54:34Z
dc.date.issued 2016-03-17
dc.identifier.other http://dx.doi.org/10.1155/2016/8356708
dc.identifier.uri http://repo.uofg.edu.sd/handle/123456789/432
dc.description Case Reports in Gastrointestinal Medicine, Volume 2016, Article ID 8356708, 3 pages en_US
dc.description.abstract Tuberculosis is a prevalent public health problem especially in the poor developing countries and results in significant mortality. Albeit tuberculosis almost always affects any organ or system of the body, abdominal tuberculosis is less frequent; moreover, tuberculous appendicitis is very rare with an incidence estimated at about 0.1–0.6% of all gastrointestinal tuberculosis.The purpose of this report was to present an unusual case of primary tuberculous appendicitis and the approach used for accurate diagnosis as well as a current update on the disease. We are reporting a 30-year-old male who presented with acute abdominal pain, fever, and vomiting and was admitted with the clinical diagnosis of acute appendicitis. Patient was investigated thoroughly and histopathologic examination was strongly suggestive of tuberculous appendicitis; however, Ziehl-Neelsen (ZN) was negative in tissue section. To confirm the diagnosis, molecular biology [polymerase chain reaction (PCR)] study was performed from the formalin fixed paraffin embedded (FFPE) appendicular tissue and revealed presence of Mycobacterium tuberculosis. As there are numerous differential diagnoses in granulomatous lesions of appendix and due to the fact that appendicular tuberculosis is a rare phenomenon; verification etiologic agent is crucial for appropriate management of the disease. en_US
dc.language.iso en en_US
dc.publisher Hindawi Publishing Corporation en_US
dc.subject Appendicular en_US
dc.subject Tuberculosis en_US
dc.subject Diagnosis en_US
dc.title The Role of PCR in Diagnosis of a Rare Appendicular Tuberculosis and Mini Literature Review en_US
dc.type Article en_US

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