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Fungal Elments in Sputum Cytology Among Active and Post_Treated Plumonary Tuberculosis Patients in Al Managil Teaching Hospital, Gezira State, Sudan (2020)

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dc.contributor.author Mustafa, Hameeda Ibrahim Ahmed
dc.date.accessioned 2021-09-22T14:32:12Z
dc.date.available 2021-09-22T14:32:12Z
dc.date.issued 2020-10
dc.identifier.uri http://repo.uofg.edu.sd/handle/123456789/3958
dc.description A Dissertation Submitted to University of Gezira as a Partial to Fulfillments for Requirement of Master of Science in Medical Labortories Sciences in Histo and Cytopathology In Department of Histo and Cytopathology Faculty of Medical Laboratory Sciences (October 2020) en_ZA
dc.description.abstract Sputum cytology is still one of the most effective and producible sample for diagnosis and evaluation of lung diseases and disorders. For this, it can used for evaluation of apportunistic fungal pathogens on pulmonary tuberculosis patients, which is of leading cause of death worldwide. On this cross sectional laboratory base study, which used to evaluate the sputum cytology for presence of opportunistic fungal elements. A total 110 early morning expectorate sample collected from the period 1/3 to 30/6/2020. 69/110 (63%) from patients come for first diagnosis to the center of T.B and HIV. Al Managil teaching hospital, and 41/110 (37%) follow-up starting from second month until six month post- treated follow up. From each sample two slides was prepared. One of them fixed immediately before air-drying in 95% ethanol and later stain by PAS technique, the other fixed after air-drying on absolute methanol and stain by Giemsa stain. Regardless to other method of fungal identification such as serology or mycological culture, only depends on microscopic identification. The study found that 95/110 (86%) was negative for fungal elements, and 15(14%) was positive, 9(8%) positive in diagnosis group and 6(5%) in follow-up group. Moreover the most common infectious agents was Candida species 9/110 (8%), 6/110 (5%) present as yeast and 3/110 (2%) as Pseudohyhae. Followed by Aspergillus species 5/110 (4%) then actinomyces species 1/110(.9%). The incidence of infection is higher in rural (82%) males (55%) farmers (36%). In the majority of the pateints with negative results for fungi MDR-TB not detected 87(79%), followed by positive for fungi and also MDR-TB not detected 15 (13.6%), then (negative and positive) for fungi and MDR-TB with high rate with the same percentage 3(2.8%), and finely very low MDR-TB 1(.9%), medium MDR-TB 1(.9%) without any detection of fungal elements. The study recommend by including fungal testing and antifungal drugs on the pulmonary TB treatment plan as possible cause of complications. en_ZA
dc.language.iso en en_ZA
dc.publisher University of Gezira en_ZA
dc.subject Tuberculosis en_ZA
dc.subject Sputum Cytology en_ZA
dc.subject Cytopathology en_ZA
dc.subject Histopathology en_ZA
dc.subject Sudan en_ZA
dc.title Fungal Elments in Sputum Cytology Among Active and Post_Treated Plumonary Tuberculosis Patients in Al Managil Teaching Hospital, Gezira State, Sudan (2020) en_ZA
dc.type Thesis en_ZA

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