dc.contributor.author |
Mamoun, Elsheikh |
|
dc.contributor.author |
Ekkehard, Doehring-Schwerdtfeger |
|
dc.contributor.author |
Christoph, Kaiser |
|
dc.contributor.author |
Ibrahim, M. Abdelrahim |
|
dc.contributor.author |
Ghorashi, M. Ali |
|
dc.contributor.author |
Doris, Franke |
|
dc.contributor.author |
Kerstin, Porrath |
|
dc.contributor.author |
Ruediger, Kardorff |
|
dc.contributor.author |
Jochen, H. H. Ehrich |
|
dc.date.accessioned |
2018-11-11T08:02:27Z |
|
dc.date.available |
2018-11-11T08:02:27Z |
|
dc.date.issued |
198 |
|
dc.identifier.uri |
http://repo.uofg.edu.sd/handle/123456789/2823 |
|
dc.description |
Pediatr Nephrol (1989)3:259-264 |
en_US |
dc.description.abstract |
Renal function was investigated in 218
school children with Schistosoma mansoni infec-
tion in the Province of Gezira in central Sudan
and in 65 Sudanese and 65 German age-matched
controls. Serum creatinine was normal in all chil-
dren. A pathological urinary protein-creatinine
ratio was found in 3% of S. mansoni-infected chil-
dren and in 5% of Sudanese controls but in none
of the European children. Characterization of
pathological proteinuria using albumin nephelom-
etry, alpha-1 microglobulin immunodiffusion
and SDS-polyacrylamide gel electrophoresis in
these children showed glomerular, tubular or
mixed glomerulotubular patterns. One, 4 and
6 months following treatment of schistosomiasis
with praziquantel, stools were re-examined; 57%
of patients were cured, 16% were found to be rein-
fected and 27% had persistent egg excretion. Six
months after therapy, pathological urinary pro-
tein-creatinine ratios were encountered in 3% of
S. mansoni patients and in none of the 34 reinves-
tigated controls. Proteinuria was similar in pa-
tients with persistent S. mansoni egg excretion
and in children cured of schistosomiasis infection.
It is concluded that there was no evidence for
S. mansoni associated glomerulonephritis in this
group of Sudanese children. The high rate of
pathological proteinuria in S. mansoni-infected
and non-infected Sudanese children may be due
to other causes. |
en_US |
dc.language.iso |
en |
en_US |
dc.publisher |
Pediatr Nephrol |
en_US |
dc.subject |
Schistosoma mansoni infection |
en_US |
dc.subject |
Renal function |
en_US |
dc.subject |
Children |
en_US |
dc.title |
Renal function in Sudanese school children with Schistosoma mansoni infection |
en_US |
dc.type |
Article |
en_US |