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Determination of Reference Values for Activated Partial Thromboplastin Time in Healthy Sudanese Adults in Gezira State, Sudan

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dc.contributor.author Mohammed Elnour Yagoub Babiker, Mohammed Elnour Yagoub
dc.date.accessioned 2018-10-17T09:31:14Z
dc.date.available 2018-10-17T09:31:14Z
dc.date.issued 2015-05
dc.identifier.uri http://repo.uofg.edu.sd/handle/123456789/2469
dc.description A Dissertation Submitted to University of Gezira in Partial Fulfillment of the Requirements for the Award of the Degree of Master of Science in Haematology and Immunohaematology Department of Haematology Faculty of Medical Laboratories Sciences University of Gezira May 2015 en_US
dc.description.abstract The haematological reference values are very important for the diagnostic orientation and treatment decision. Thereference values are influenced by many environmental and genetic factors. The use of Western reference value for interpretation of laboratory results in Gezira State may be differ and misdiagnosis may occur. This was prospective analyticalcross sectional study carried out in Gezira State from September 2014 to March 2015. The aim of the study was to establish the reference values for activated partial thromboplastin time (APTT) in healthy Sudanese adults living in Gezira State. A total of 657 (281 males and 376 females) healthy volunteers their ages ranged between 18 – 60 years, were randomly selected according to inclusion and exclusion criteria. 2 ml of blood samples were collected into tri-sodium citrate containers, platelets poor plasma were obtained by centrifugation, then after running of commercial controls, all samples were estimated for APTT using Coatron M4 coagulometer device according to manufacturer's instructions. The data was analyzed using Statistical Package for Social Sciences (SPSS) computer program (version 16.0). The results obtained in this study revealed that the reference values for APTT among healthy Sudanese adults living in Gezira State were similar to standard reference values, but the upper limit of APTT in this study was significantly higher (26.3 – 42.7 seconds). Significant difference was enrolled when comparing the values obtained in this study with other populations. In this study there were significant difference in APTT values between study population according to their age, locality, occupation and female’s marital status, while there were no significant differences according togender, tribe, education and number of birth. The important recommendations in this study were to use the reference values obtained in this study in medical practice in Gezira State instead of Western values quoted from textbooks and to establish reference values for all laboratory tests in Sudan. en_US
dc.description.sponsorship Bakri Yousif Mohammed Nour Main supervisor Albadawi Abdelbagi Talha Co supervisor Muawia Mohammed Ahmed Co supervisor en_US
dc.language.iso en en_US
dc.publisher University of Gezira en_US
dc.subject thromboplastin en_US
dc.title Determination of Reference Values for Activated Partial Thromboplastin Time in Healthy Sudanese Adults in Gezira State, Sudan en_US
dc.type Thesis en_US

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